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Pharmaceutical Chemistry Dissertations and Theses
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Some features of this site may not work without it. Pharmaceutical Chemistry Dissertations and Theses Browse by. The synthesis of intermediates for conversion to cortisone analogues Jackson, Peter H, phd thesis in pharmaceutical chemistry. University of Kansas Chemotherapeutic agents in the quinolinol series Edgerton, William Howard University of Kansas Design of Intratumoral Immunostimulant Formulations Mihalcin, Melissa Marie University of Kansas Tumors possess myriad suppressive mechanisms that facilitate evasion of the immune system.
Immunotherapy aims to stimulate immune Brain delivery of BDNF and a monoclonal antibody for the treatment of neurodegenerative animal models Kopec, Brian Matthew University of Kansas There are a large number of protein-based therapeutics biologics that are FDA approved and available on the market for a number of diseases, and the number of biologics being approved every year has tripled in the past Physicochemical stability and effector function of IgG4-Fc: impact of photo-induced chemical modification and glycosylation Kang, Huan University of Kansas Immunoglobulin gamma monoclonal antibodies are glycoproteins that have emerged as powerful and promising protein therapeutics.
During the process of production, storage and transportation, phd thesis in pharmaceutical chemistry, exposure to ambient light is Analysis of Spa33 and its Role in T3SS Cytoplasmic Sorting Platform of Shigella Skaar, Ryan Richard University of Kansas Enteric infections, particularly those leading to diarrhea, phd thesis in pharmaceutical chemistry, can profoundly disrupt intestinal function and have a major impact on global mortality and morbidity rates.
Preservation of Human T Cell Membrane Integrity after Drying and Rehydration Langford, Alex University of Kansas The biopharmaceutical industry has reached new frontiers in its ability to produce complex novel modalities for therapeutic application.
Novel cell-based therapies offer a promising treatment for cancer by enabling T cells Method for Simultaneous Quantitation of Free Carrier Protein and Free Polysaccharide in Glycoconjugate Vaccines by High Performance Liquid Chromatography Hartzel, Ian University of Kansas Disease caused by bacterial infections affect children and adults worldwide can be potentially life-threatening.
Bacterial strains, such as Staphylococcus aureus and Streptococcus pnueumoniae pneumococcusexpress capsular Development and biophysical characterization of a hyaluronic acid — vitamin E conjugate as a subcutaneous delivery platform Moulder, phd thesis in pharmaceutical chemistry, Kenneth Ryan University of Kansas The inherent properties of protein therapeutics e.
high molecular weight, charged, conformationally dependent has historically limited their administration to parenteral routes which presents new challenges to their A run Design-of-Experiment DoE was conducted to evaluate the effects of the type of core and Design of Antigen-Specific Immunotherapies Through Modulation of Peripheral Tolerance Pathways Christopher, Matthew Alexander University of Kansas Current therapies for autoimmune diseases phd thesis in pharmaceutical chemistry specificity for the offending immune cell population resulting in a wide range of side effects and weakening of the immune system.
This presents a clear need for antigen-specific Analytical characterization and formulation development of a trivalent subunit rotavirus vaccine for the developing world Agarwal, Sanjeev University of Kansas Although live attenuated, orally delivered rotavirus RV vaccines are available globally to provide protection against enteric RV disease, efficacy is substantially lower in low to middle income settings leading to interest Chemical and Physical Instability of Monoclonal Antibodies Induced by Metal-catalyzed Carbonylation Yang, Yi University of Kansas In the pharmaceutical industry, recombinant phd thesis in pharmaceutical chemistry antibodies mAbs have become a major focus of therapeutic drug development due to their broad applications in many disease areas.
During manufacturing and storage of Utilizing IgG1 Fc As An Immunomodulator White, Derek Robert University of Kansas Antibody-based therapeutics are a rapidly expanding class of biopharmaceuticals. The number of approved antibody-based therapeutics by the FDA and EMA has more than doubled in the last five years, and they are expanding The Degradation of 4-Morpholinoaniline in Aqueous Solution Forseth Millard, Kristen University of Kansas The reactivity of 4-morpholinoaniline with water was examined in aqueous solutions at pH 1 — 4.
Two dissociation constant values were identified for 4-morpholinoaniline using spectrophotometric titration: pKa1, which was Characterization, Stabilization and Formulation Design of IgG and Secretory IgA Monoclonal Antibody Candidates during Storage and Administration Hu, Yue University of Kansas ABSTRACT Monoclonal antibodies mAbs have become a class of therapeutic protein-based drugs of high importance for treating numerous human diseases.
As a complex, delicate three dimensional molecule, a mAb can be sensitive Targeted Proteomics for Exosome Analysis phd thesis in pharmaceutical chemistry Its Application to Develop Blood Markers of Liver Drug-Metabolizing Enzymes Doyle, Laura Michelle University of Kansas Two main routes of drug elimination include renal excretion via the kidney and metabolic degradation via metabolizing enzymes DMEs in the liver, followed by renal excretion or biliary elimination of the now more polar Degradation of therapeutic proteins: Screening methods and identification of epimerized amino acids and local conformational changes in light exposed proteins Bommana, Rupesh University of Kansas Protein-based pharmaceuticals are a fast growing class of therapeutics, which are widely used in the treatment of phd thesis in pharmaceutical chemistry diseases such as cancers and autoimmune diseases.
Proteins are susceptible to multiple degradation Antibody-based therapeutics continue to be a fast growing field in pharmaceutics due to their increased selectivity for a specific target over small molecule drugs. Antibody solutions are often formulated at high protein Strategies to improve the immunogenicity of subunit vaccine candidates Wei, Yangjie University of Kansas Subunit vaccines contain highly defined phd thesis in pharmaceutical chemistry components of a pathogen that are capable of eliciting protective immunity.
They possess several advantages over other vaccine types e. live attenuated and inactivated Search KU ScholarWorks. This Collection. Author Mitra, Pallabi 2 Yang, Yi 2 Agarwal, Sanjeev 1 Al-Hossaini, Abdullah 1 Al-Kinani, Khalid Kadhem Abed View More Subject Pharmaceutical sciences Pharmaceutical chemistry 23 Analytical chemistry 12 Chemistry 12 View More Date Issued - - 16 - 7.
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phd thesis in pharmaceutical chemistry The University of Arizona (UA) is the flagship institution in the State of Arizona and offers graduate programs in more than areas of study/10() Janice Reyes. Published: 12 Jun Thanks for your help! I like everything Phd Thesis In Pharmaceutical Chemistry about the paper – the content, formatting, and Phd Thesis In Pharmaceutical Chemistry especially I like the ending paragraph. It is so passionate and creative that I was impressed. Thanks again! Pharmaceutical Chemistry Dissertations and Theses. Browse by Search within this collection: Go Recent Submissions. The synthesis of intermediates for The study in this thesis systemically investigated the application of core/shell technique to improve powder compactability. A run Design-of-Experiment (DoE) was conducted to evaluate the
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